Vitamin B6 occurs in three forms–pyridoxine, pyridoxamine, and pyridoxal. B6 is absorbed in the massive intestine. The muscle stores roughly 75-80 % of the vitamin while the living stores approximately 5-10 %.
B6 is recommended for transaminations, ammonia release,, side chain cleavage reactions, dehydratases and decarboxylations. The aldehyde group of its functions as a Schiff base to react with the amino groups of amino acids. It basically acts to shuttle nitrogen among compounds.
Functions- The 3 types of B6 can all be converted on the coenzyme PLP that aids in transamination and protein metabolism. PLP is vital for glycogen degradation; it also helps with the development of the neurotransmitter, serotonin, the nonprotein portion of hemoglobin (heme), nucleic acids, and lecithin. Vitamin B6 is essential for the metabolic rate of tryptophan to niacin.
General Reactions:
· Transaminations These responses are necessary to reuse as well as reuse nitrogen in the body. They are the first phase of amino acid catabolism as well as the last stage in the synthesis of nonessential amino acids. Example: a-ketoglutarate + asparate glutamate + oxaloacetate
· Serine/ Threonine Deamination (Dehydratases) This response provides the production of the a keto acids of serine as well as threonine via oxidative removal of N as ammonia Example: Serine a-keto-serine + NH4+
· Decarboxylation These reactions frequently occur on the neuroactive amines of seratonin, tyramine, histamine, and GABA. Additionally they are crucial in porphyrin synthesis, intermediates in the synthesis of sphingomyelin, taurine and lecithin, and himalayan ice hack ingredients list (https://jobhop.co.uk/) for the breakdown as well as desulfuration of cysteine.
· Glycogen Phosphorylase fifty % of all B6 in the body is bound to glycogen phosphorylase though the value is unknown. The reaction is vital for recycling of folate and is as follows: