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Bioorg Med Chem Lett 17, 1466-1470. Byeon SR, Jin YJ, Lim SJ, Lee JH, Yoo KH, Shin KJ, Oh SJ, Kim DJ (2007) Ferulic acid and benzothiazole dimer derivatives with significant binding affinity to beta-amyloid fibrils. Bioorg Med Chem Lett 17, 4022-4025. Dolphin GT, Ouberai M, Dumy P, Garcia J (2007) Designed amyloid beta peptide fibril -a device for highthroughput screening of fibril inhibitors. Expert Opin Emerg Drugs 17, 43-60. Di Santo R, Costi R, Cuzzucoli CG, Pescatori L, Rosi F, Scipione L, Celona D, Vertechy M, Ghirardi O, Piovesan P, Marzi M, Caccia S, Guiso G, Giorgi F, Minetti P (2012) Design, synthesis and composition-activity romantic relationship of NAryl-naphthylamine derivatives as amyloid aggregation inhibitors. Science 306, 865-869. Lin SJ, Shiao YJ, Chi CW, Yang LM (2004) Abeta aggregation inhibitors. Bioorg Med Chem Lett 16, 1076-1079. Inbar P, Li CQ, Takayama SA, Bautista MR, Yang J (2006) Oligo(ethylene glycol) derivatives of thioflavin T as inhibitors of protein-amyloid interactions.

J Am Chem Soc 128, 3522-3523. Inbar P, Yang J (2006) Inhibiting protein-amyloid interactions with compact molecules: A area chemistry tactic. Dolphin GT, Dumy P, Garcia J (2006) Control of amyloid beta-peptide protofibril development by a made template assembly. Biochemistry 47, 1984-1992. Bravo R, Arimon M, Valle-Delgado JJ, Garcia R, Durany N, Castel S, Cruz M, Ventura S, Fernandez-Busquets X (2008) Sulfated polysaccharides boost the assembly of amyloid beta(1-42) peptide into steady fibrils of reduced cytotoxicity. Curr Med Chem 19, 4157-4174. Ryan TM, Friedhuber A, Lind M, Howlett GJ, Masters C, Roberts BR (2012) Small amphipathic molecules modulate secondary construction and amyloid fibril-forming kinetics of Alzheimer disorder peptide Abeta(1-42). Biochem Soc Trans 33, 543-547. Lee KH, Shin BH, Shin KJ, Kim DJ, Yu J (2005) A hybrid molecule that prohibits amyloid fibrils and alleviates neuronal toxicity induced by beta-amyloid (1-42). Biochem Biophys Res Commun 328, 816-823. Schwarzman AL, Tsiper M, Gregori L, Goldgaber D, Frakowiak J, Mazur-Kolecka B, Taraskina A, Pchelina S, Vitek MP (2005) Selection of peptides binding to the amyloid ␤-protein reveals potential inhibitors of amyloid development. J Med Chem 55, 8483-8492. Liu R, Su R, Liang M, Huang R, Wang M, Qi W, He Z (2012) Physicochemical methods for inhibition of amyloid fibril formation: An overview of the latest advancements.

Amyloid 18, 119-127. Lukiw WJ (2012) Amyloid beta (Abeta) peptide modulators and other present-day treatment tactics for Alzheimer’s disease (Ad). Neurobiol Dis 28, 251-260. Necula M, Kayed R, Milton S, Glabe CG (2007) Small molecule inhibitors of aggregation point out that amyloid beta oligomerization and fibrillization pathways are independent and distinct. Chembiochem 8, 985-988. Austen BM, Paleologou KE, Ali SA, Qureshi MM, Allsop D, El-Agnaf OM (2008) Designing peptide inhibitors for oligomerization and toxicity of Alzheimer’s beta-amyloid peptide. Eur J Med Chem 45, 1359-1366. Matharu B, El-Agnaf O, Razvi A, Austen BM (2010) Development of retro-inverso peptides as anti-aggregation prescription drugs for beta-amyloid in Alzheimer’s disorder. Nat Chem Biol 4, 197-199. Lee JH, Byeon SR, Lim SJ, Oh SJ, Moon DH, Yoo KH, Chung BY, Kim DJ (2008) Synthesis and analysis of stilbenylbenzoxazole and stilbenylbenzothiazole derivatives for detecting beta-amyloid fibrils. Chem Biol Drug Des 67, 27-37. Byeon SR, Lee JH, Sohn JH, Kim DC, Shin KJ, Yoo KH, Mook-Jung I, Lee WK, Kim DJ (2007) Bis-styrylpyridine and bis-styrylbenzene derivatives as inhibitors for Abeta fibril formation. Bioorg Med Chem 15, 1160-1167. Sato J, Takahashi T, Oshima H, Matsumura S, Mihara H (2007) Design of peptides that variety amyloid-like fibrils capturing amyloid beta1-42 peptides.

Peptides 31, 1866-1872. Suzuki M, Takahashi T, Sato J, Mie M, Kobatake E, Mihara H (2010) Designed quick peptides that sort amyloid-like fibrils in coassembly with amyloid beta-peptide (Abeta) minimize the toxicity of Abeta to neuronal PC12 cells. Ryan TM, Griffin MD, Teoh CL, Ooi J, Howlett GJ (2011) High-affinity amphipathic modulators of amyloid fibril nucleation and elongation. J Biol Chem 286, 3209-3218. Ortega A, Rincon A, Jimenez-Aliaga KL, Bermejo-Bescos P, Martin-Aragon S, Molina MT, Csaky AG (2011) Synthesis and analysis of arylquinones as BACE1 inhibitors, beta-amyloid peptide aggregation inhibitors, and destabilizers of preformed beta-amyloid fibrils. ChemMedChem 4, 1488-1494. Madine J, Wang X, nude-Cam-Model Brown DR, Middleton DA (2009) Evaluation of beta-alanine- and GABA-substituted peptides as inhibitors of illness-linked protein aggregation. Front Biosci 13, 4039-4050. Esteras-Chopo A, Morra G, Moroni E, Serrano L, Lopez de la PM, Colombo G (2008) A molecular dynamics research of the conversation of D-peptide amyloid inhibitors with their target sequence reveals a probable inhibitory pharmacophore conformation.

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